Everything about e-cigarettes, this article can tell you

Q1: Will electronic cigarettes lure non-smokers to gradually transition to smoking cigarettes?

This statement takes advantage of the assumptions of many people: e-cigarettes are also vaping, and if they are not addicted to smoking, they will naturally seek more exciting cigarettes, so what is the truth?



Jacques Le Houezec, a neuroscientist at the French National Institute of Medicine, analyzed EU poll data in detail. The results show that only 0.09% of non-smokers will use e-cigarettes every day after trying e-cigarettes. stop.

In terms of attitudes towards e-cigarettes, governments around the world have emphasized its impact on young people. For example, the FDA’s recent news about banning certain e-liquid flavors to prevent teenagers from becoming addicted to e-cigarettes is a hot topic in major American media, but in fact, Whether e-cigarettes can lead to addiction among teenagers is still controversial.

Four representative surveys of UK teenagers in 2014 showed that 8% of young people had tried e-cigarettes at least once, but only 2% of them used e-cigarettes regularly, and most of these people had a history of smoking. In a survey of about 9,000 11- to 16-year-olds in Wales, only 54 non-smokers regularly used e-cigarettes.



Not just the UK, but the Journal of the American Medical Association followed up with 3,300 participants in ten Los Angeles high schools, and 7% had used e-cigarettes at least once in the past 30 days. But when the researchers looked at 2,530 subjects who had never used tobacco at the start of the study, only 222 of them (8.7 percent) said they had tried e-cigarettes.

This tells us that while young people are trying e-cigarettes, and the percentage who say they have tried it is on the rise, only a very small number of young non-smokers are regularly drawn to these products.

Q2: I heard that smoking electronic cigarettes will inhale heavy metals. What’s the matter?

The claim that the heavy metals in e-cigarettes exceed the standard mainly comes from a paper by Johns Hopkins University, as shown in the figure below.

But recently, a study published in the SCI journal “Inhalation Toxicology” strongly refuted this assertion.



Prof. Konstantinos Farsalinos from the University of Patras, Greece, and Prof. Brad Rodu, from the University of Louisville, USA, pored over the paper and found that the Johns Hopkins researchers had miscalculated the daily intake of vapers, and they concluded that The premise of excessive heavy metals is that vapers inhale e-cigarettes at least 24 hours a day – people breathe about 17,000 times a day, and according to a large number of surveys done by relevant agencies, each Vaper smokes e-cigarettes about 600 times a day on average.

So will these 600 mouthfuls of inhalation cause excessive heavy metal intake? The two professors used three internationally recognized heavy metal safety standards (PDE, MRL and REL) respectively to calculate the heavy metal content in electronic cigarettes, and came up with such a table.



This table lists all the heavy metal elements contained in e-cigarettes: aluminum, chromium, cadmium, copper, lead, iron, nickel, etc., and the conclusion is that even if the highest standard of heavy metal content in the Johns Hopkins paper is used (far right of the table), it is also almost impossible to inhale excessive heavy metals through e-cigarettes.

Everyone pay attention to the far right part of the table. A vaper who smokes 1.5 million grams of e-liquid every day will only inhale aluminum that exceeds the safety standard. Cadmium is 15,000 grams, copper is 588 grams, lead is 135 grams, and the lowest is nickel, which also absorbs 17 grams.

What is the concept of smoking 17 grams of e-liquid a day? Let’s take MOTI as an example. The amount of e-juice in a pod is 1.8 ml. We calculate the weight of glycerol, which has the largest specific gravity, and the weight of e-juice will not exceed 2.5 grams, which is equivalent to letting a vaper smoke 7 cigarettes a day. bomb.



The editor has been in contact with a lot of vapers. It is rare to smoke 2-3 pods a day. Smoking 7 pods should be able to apply for the Guinness World Records.

So far, we can conclude that it is impossible to ingest excessive heavy metals through electronic cigarettes, especially small cigarettes. Unless you have the intention to do toxicology experiments on yourself, you can only inhale excessive nickel.

Q3: Electronic cigarettes also have nicotine, why is it less harmful than cigarettes?

Many people’s fear of nicotine may come from the same saying: a drop of nicotine can kill a horse. This statement often appears in various public service advertisements for smoking cessation, but in fact, it has little to do with the actual harm caused by nicotine to the human body.

As a ubiquitous addictive substance in nature, many vegetables we are familiar with, such as tomatoes, eggplants, and potatoes, contain trace amounts of nicotine. It is especially worth mentioning that wolfberry, a health treasure in the eyes of many people, also contains nicotine. But the content is very small.



“Putting wolfberry in a thermos cup will also drink nicotine”

Injecting nicotine is indeed very toxic. Extracting nicotine from 15-20 cigarettes and injecting it into a vein can cause death. Note, however, that inhaling nicotine-containing smoke and injecting it intravenously are not the same thing.

Studies have shown that the nicotine absorbed by the lungs when smoking only accounts for 3% of the total, and these nicotine will be rapidly degraded after entering the human body and excreted through sweat, urine, etc. This is why it is difficult for us to cause nicotine poisoning due to smoking.

Evidence from modern medicine shows that the serious consequences of cigarettes, such as lung cancer, emphysema and cardiovascular disease, are basically all from cigarette tar, and the harm of nicotine to the human body cannot be compared with it, Public Health England (PHE) released The report mentioned that tar-free e-cigarettes are at least 95% less harmful than cigarettes, and there is no difference in nicotine content between the two.

Q4: But I heard that nicotine has adverse effects on cardiovascular and brain development?

This statement is true, but you may be overestimating its actual harm. As a stimulant, after nicotine enters the human body, it will stimulate peripheral vasoconstriction, resulting in faster heartbeat, higher blood pressure and faster breathing, increasing the risk of cardiovascular diseases such as hypertension and stroke.

It’s by no means harmless, but virtually any stimulant carries the same health risks, including another common stimulant in life: caffeine.

Caffeine, like nicotine, is a stimulant that acts on the central nervous system. The effect of nicotine on the cardiovascular system is almost the same as that of caffeine. However, we will not see signs indicating health risks on the packaging of any kind of coffee. The caffeine is difficult to actually cause health problems.



Some friends may say that they do not have the habit of drinking coffee, but in fact, many Chinese people who are used to drinking tea are exposed to caffeine every day, because the caffeine content in green tea is even higher than that in coffee. Therefore, if you drink tea regularly, it is difficult to say that the trace amount of nicotine in e-cigarettes will significantly affect your cardiovascular and cerebrovascular health.

The effects of nicotine on teenage brain development, especially in the processing of language and memory, are indeed supported by some medical evidence. However, caffeine can also affect brain development. Therefore, while banning teens from vaping, they should also be urged to drink less or no coffee.

The current exaggerated and untrue claims about the health hazards of nicotine originated from the public health campaigns in Europe and the United States in the 1960s. At that time, governments in various countries deliberately exaggerated the toxicity of nicotine in order to promote smoking cessation. In fact, whether trace amounts of nicotine are good or bad for the human body is still controversial in the medical community: for example, the Royal Society of Public Health (RSPH) in the United Kingdom has highlighted some of the medical benefits of nicotine, such as the treatment of Parkinson’s, Alzheimer’s and attention deficit disorder. and many more.

Although the old saying “to talk about toxicity without dose is a hooligan”, we still have to be careful about the possible health risks of nicotine. If you are not addicted to smoking, don’t try all nicotine inhalation devices, including e-cigarettes.

Q5: Although the nicotine in e-cigarettes is not very harmful, is the essence in the e-liquid toxic?

“Perfume is toxic” is also an old rumor about e-cigarettes. Compared with nicotine and heavy metals, it is more confusing. This is because, although the artificial flavors in more than 8,000 known e-liquids have reached food-grade standards, it means that they are non-toxic when placed in food, and the toxicity of inhalation after atomization has not been certified. The exaggerated claim that vaping produces toxicity has been rampant in recent years. The most typical claim is that the diacetyl in e-cigarette flavors can cause popcorn lung.



How is the truth?

In 2015, a study from Harvard University analyzed e-liquids. The results showed that 75 percent of the scented liquids they tested contained a chemical called diacetyl, an artificial flavor with a buttery flavor that was discovered in 2000. It is believed to be the cause of eight popcorn factory workers suffering from a rare lung disease called bronchiolitis obliterans, also known as “popcorn lung.”

“Popcorn lung” is an irreversible obstructive lung disease in which the bronchioles are narrowed and blocked due to inflammation or fibrosis. There are many causes of the disease, such as viral infections, transplant rejection, and exposure to toxic chemicals including chlorine, ammonia, and ozone. The above-mentioned eight workers are typical cases affected by the toxic environment. It is because they have been exposed to high concentrations of diacetyl gas for a long time that they developed this disease.

In this regard, Professor Konstantinos Farsalinos of the University of Patras in Greece found 159 e-liquid samples, 74.2% of which contained diacetyl. Only 56 micrograms per day, well below the National Institute for Occupational Safety and Health (NIOSH) safety standards, and 100 times lower than the exposure from cigarettes.



Interestingly, although the levels of diacetyl in cigarettes are much higher than in e-cigarettes, there have been no known cases of smokers developing popcorn lung.

In addition to the famous “popcorn lung theory”, due to the very complex composition of flavors, many media have also made other claims, such as the cytotoxicity of flavors exceeds that of cigarettes, and the substances in flavors can greatly damage lung and heart function. The report on e-cigarettes released by Public Health England in 2018 cracked down on these claims one by one.

According to the report, many media claimed that cinnamon-flavored e-liquids have strong cytotoxicity, and tobacco-flavored e-liquids have high levels of nitrosamines, but the toxic substances in these e-liquids are orders of magnitude lower than cigarettes (orders of magnitude).

The report pointed out that many experiments to prove the cytotoxicity of flavors did not use atomized e-liquid, but directly exposed cells to toxic molecules in flavors. -15%, with different concentrations of toxic substances, the cytotoxicity will be very different. Even so, the report found, it was far less toxic than cigarettes. As the old saying goes, talking about toxicity without dose is hooliganism.

Although the medical community has not provided definite evidence of fragrance toxicity, out of the prudent attitude of scientific research, the report still points out that due to the complex composition of fragrances, there are still certain preventable risks after inhalation, and more experiments are needed. To find out its effects on the human body after inhalation.

Q6: In addition to nicotine, I heard that electronic cigarettes can also inhale formaldehyde, so the carcinogenicity exceeds that of ordinary cigarettes. What is going on?

This statement was first seen in a paper in the New England Journal of Medicine. Its experimental data are not completely unreliable, but there is a prerequisite, dry burning.

The so-called dry burning refers to the phenomenon that the heating wire continues to heat the oil-conducting cotton after the e-liquid is exhausted when using high-power vape. Experiments by Greek scientist Konstantinos Farsalinos in 2016 showed that the conclusion on the carcinogenicity of e-cigarettes was drawn after frequent dry burning of e-cigarettes in the laboratory. However, in real life, dry burns are easily discernible by users, so the inhalation of aldehydes is much lower than laboratory data.

In addition, Dr. Farsalinos’ team also tested that the concentration of aldehydes released by e-cigarettes is related to the voltage, and the release equivalent of aldehydes at 5.0V is 7 to 8 times that of 4.2V.



The relationship between the release amount of formaldehyde, acetaldehyde, acrolein and acetone and the voltage of electronic cigarette.

As can be seen from the above figure, when the voltage is below 4.0v, the release of aldehydes is extremely small. For example, the formaldehyde inhaled by 50 puffs of electronic cigarettes is less than 10 micrograms, and the harm is almost negligible.

It can be said that the use of high-power vape may indeed lead to excessive inhalation of formaldehyde due to dry burning, but the voltage of small smoke is generally lower than 4.0V, so it is difficult to say how many health risks are caused by inhaled trace formaldehyde.

Q7: Since e-cigarettes are so much less harmful than cigarettes, why does Hong Kong still completely ban e-cigarettes?

In October last year, Hong Kong Chief Executive Carrie Lam said in her 2018 policy address that e-cigarettes would be banned in Hong Kong. And there are reports that the Hong Kong medical community has long called for the ban on e-cigarettes, and has also established a major alliance to ban e-cigarettes, urging the SAR government to ban emerging tobacco products such as e-cigarettes and heated cigarettes as soon as possible.

This news may be the direct reason why many friends have turned sour about e-cigarettes in recent days. It is true that e-cigarettes are harmful to health, and it is true that Hong Kong bans e-cigarettes. In addition to Hong Kong, 16 countries including Singapore, Brazil, and the Philippines have also banned the sales of e-cigarettes. But the strange thing is that the United States, Britain, France and other countries whose medical level exceeds that of Hong Kong have not banned e-cigarettes.

This is not because these countries are unaware of the risks of vaping, but because public health policymaking must weigh the pros and cons.



The premise of Hong Kong’s comprehensive ban on e-cigarettes is that it is the world’s leading tobacco control policy. The data shows that from the birth of Hong Kong’s first anti-smoking law in 1982 to the revision of the “Smoking (Public Health) Ordinance” in 2012, smoking is prohibited in places with ceilings, and the proportion of smokers over the age of 15 in Hong Kong is now controlled below 10%. The proportion of young people aged between 15 and 19 who smoke has dropped to 1%, far exceeding the level of tobacco control in Europe and the United States. The harm of cigarettes to public health in Hong Kong has been effectively controlled.



Under this premise, although the harm of electronic cigarettes is far less than that of cigarettes, due to the small base of smokers, it will not play a significant role in reducing the proportion of smokers in the population, but may cause young people to be induced. Therefore, A blanket ban is the option in the best interests of the majority.

In countries such as the United Kingdom and the United States, the proportion of smokers is much higher. As a harm reduction product that is far less harmful than cigarettes, electronic cigarettes have a significant effect on reducing the number of smokers, especially the harm of second-hand smoke. Therefore, although the FDA has issued regulatory measures for electronic cigarettes, it has never mentioned a complete ban.

It is worth mentioning that although the Hong Kong medical community has emphasized the harm of electronic cigarettes, no one has ever said that electronic cigarettes are more harmful than cigarettes.

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AAAVape or say Triple-A vape was started its vape journey 10 years ago, which is the combination of Core R&D development and service spirits.

Unlike most vape company focused on brand marketing, AAAVape pays more attention to coil technology. About Five years ago, The Leader of AAAvape started the tough work for high-density organic cotton material, after thousands of failure AAAVape acquired its own Ccoil Technology.

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